Identification of chemical compounds of 70% ethanol extract of chinese betel leaves (Peperomia pellucida) from blora regency
Article Sidebar
Main Article Content
Abstract
Indonesia is rich in various plants, one of which is the Chinese Betel (Peperomia pellucida). This study aims to identify the chemical compounds of 70% ethanol extract from Chinese betel leaves in Blora Regency. The identification method is by laboratory observation with Thin Layer Chromatography (TLC). The results of the TLC test with the highest or best values are saponins, tannins, triterpenoids which can be seen by looking at the difference between the high points of the stains on the sample and the comparator. The active content in saponins, tannins and triterpenoids functions as a source of antibacterials, increasing the immune system. Flavonoids also have anti-inflammatory content (anti-inflammatory on the skin), as antioxidants and as histamine. Saponins as antibacterials with a mechanism that reacts with porins (transmembrane proteins) on the outer membrane of the bacterial cell wall, forming strong polymer bonds that damage the porins and can inhibit the growth of antibacterials.
Article Details
References
J. Waluyo, K. Fikri, dan F. S. Cahyani, “Eugenia polyantha leaf extract as an antidiabetic alternative medicine on Rattus norvegicus,” Edubiotik J. Pendidikan, Biol. Dan Terap., vol. 8, no. 01, hal. 11–16, 2023, doi: https://doi.org/10.33503/ebio.v8i01.2651.
S. Phongtongpasuk dan S. Poadang, “Extraction of antioxidants from Peperomia pellucid a L . Kunth,” Thammasat Int. J. Sci. Technol., vol. 19, no. 3, 2014.
I. D. Riris, T. Juwitaningsih, D. Rosa, M. Damanik, dan A. Silalahi, “Study of Phytochemicals, Toxicity, Antibacterial Activity of Ethyl Acetate Leaf Extract Extract (Peperomia pellucida L),” Indones. J. Chem. Sci. Technol., vol. 3, no. 2, 2020, doi: https://doi.org/10.24114/ijcst.v3i2.19532.
H. Prasetyo, M. C. Padaga, dan M. E. Sawitri, “Kajian kualitas fisiko kimia daging sapi di pasar kota malang,” J. Anim. Prod. Sci. Technol., vol. 8, no. 2, hal. 1–8, 2013, doi: https://doi.org/10.21776/ub.jitek.2013.008.02.1.
Kemenkes RI, “Farmakope Herbal Indonesia 2017,” Kementerian Kesehatan RI, 2017.
N. Maharani, V. Haksadjiwo, R. S. Dwi, G. Anggraini, dan B. Nuryadi, “Antibacterial Activity of Suruhan Leaf Extract (Peperomia pellucida L) Against Staphylococcus aureus,” Sriwij. Journalof Dent., vol. 4, no. 1, hal. 1–10, 2023, doi: https://doi.org/10.32539/sjd.v4i1.41.
H. Wijaya, N. Novitasari, dan S. Jubaidah, “Comparison of Extraction Methods on the Yield of Sea Hair Leaf Extract (Sonneratia caseolaris L. Engl),” J. Ilm. Manuntung, vol. 4, no. 1, hal. 79–83, 2018, doi: https://doi.org/10.51352/jim.v4i1.148.
Ihwan, A. Khumaidi, A. D. Putri, R. Primadia, A. Syamsidi, dan K. Khaerati, “Standardization of Ethanol Extract of Dioscorea alata L . Variety of Paoateno from Banggai Islands District , Central Sulawesi,” J. Farm. Galen. (Galenika J. Pharmacy), vol. 9, no. 2, hal. 208–223, 2023, doi: 10.22487/j24428744.2023.v9.i2.16065.
A. I. N. Widyastuti, Wulandari, dan A. F. Masduqi, “Antioxidant activity test of ethanol extract of red algae (Kappaphycus alvarezii) green variety from north coasts of Jepara district with DPPH method,” J. Heal. Manag. Pharm. Explor., vol. 1, no. 1, hal. 1–8, 2023, doi: https://doi.org/10.52465/johmpe.v1i1.133.
A. Salsabila, S. Febriana, dan U. M. Surakarta, “Development Of Guidelines For Micro Teaching In Early Children Education Faculty Of Universitas Muhammadiyah Surakarta,” Cakrawala Dini J. Pendidik. Anak Usia Dini, vol. 12, no. 2, hal. 159–167, 2021, doi: 10.17509/cd.v12i2.37463.
P. Viogenta, L. Megasari, dan L. Susanti, “Bioautography and FTIR Analysis of Ethanol Fraction Morel Berry Root ( Physalis angulata L .) Against Staphylococcus epidermidis and Pseudomonas aeruginosa,” Tradit. Med. J., vol. 27, no. December, hal. 4–10, 2022, doi: 10.22146/mot.78171.
M. A. P. Suharto, H. J. Edy, dan J. M. Dumanauw, “Isolasi Dan Identifikasi Senyawa Saponin Dari Ekstrak Metanol Batang Pisang Ambon(Musa Paradisiaca Var. Sapientum L.),” PHARMACON, vol. 1, no. 2, hal. 86–92, 2012, doi: https://doi.org/10.35799/pha.1.2012.914.
B. Sopiah, H. Muliasari, dan E. Yuanita, “Skrining Fitokimia dan Potensi Aktivitas Antioksidan Ekstrak Etanol Daun Hijau dan Daun Merah Kastuba ( Phytochemical Screening and Potential Antioxidant Activity of Ethanol Ekstract of Green Leaves and Red Leaves Kastuba ),” J. ILMU KEFARMASIAN Indones., vol. 17, no. 1, hal. 27–33, 2019.
S. D. Marliana dan V. Suryanti, “Skrining Fitokimia dan Analisis Kromatografi Lapis Tipis Komponen Kimia Buah Labu Siam ( Sechium edule Jacq . Swartz .) dalam Ekstrak Etanol The phytochemical screenings and thin layer chromatography analysis of chemical compounds in ethanol extract of la,” Asian J. Nat. Prod. Biochem., vol. 3, no. 1, hal. 26–31, 2005, doi: 10.13057/biofar/f030106.
A. Rahmawatiani, D. Mayasari, dan A. C. Narsa, “Kajian Literatur: Aktivitas Antibakteri Ekstrak Herba Suruhan (Peperomia pellucida L.),” Proceeding Mulawarman Pharm. Conf., hal. 117–124, 2020, doi: 10.25026/mpc.v12i1.401.
Z. Farda, T. P. Rahayu, N. Zukhruf, dan W. Kiromah, “Formulation and Physical Evaluation of Papaya Leaf ( Carica papaya L .) Ethyl Acetate Fraction Cream Preparation as Anti Acne Against Propionibacterium acne Bacteria,” J. Pijar MIPA, vol. 19, no. 2, hal. 295–301, 2024, doi: 10.29303/jpm.v19i2.6146.