W/O/W type lotion formulation of “arum manis” mango (Mangifera indica L.) pell as antioxidant
Main Article Content
Abstract
Arum manis mango peel contains compounds, namely flavonoids. Flavonoid compounds act as natural antioxidants. The weakness of flavonoid compounds is that they are not stable to the influence of high temperature and light intensity, so that the arum manis mango peel extract is made in the form of lotion type W/O/W. This study aims to determine the physical characteristics and stability of the W/O/W type emulsion form optimum formula in double emulsion preparations and lotion preparations, determine the stability of W/O/W type lotion preparations during storage using the cycling test method and determine the IC50 value in the optimum formula. lotion preparation type W/O/W. The optimum formula for double emulsion type W/O/W is found in formula 5 with a ratio of primary emulsion: secondary emulsion (80%:20%) with span 80 (10%) and tween 20 (5%) concentrations while the optimum formula for lotion preparations found in formula 3 with a ratio of double emulsion type W/O/W: lotion base (80%:20%) with a concentration of stearic acid (5%), cetyl alcohol (2.5%) and glycerin (10%). In the antioxidant activity of lotion preparations, the IC50 value was 136.543 ppm and the stability test on the cycling test method had an unstable form.
Article Details
References
Wulandari and I. Sulistyarini, “Antibacterial activity test of extract ethanol mango arumanis skin ( Mangifera indica L ) on Methicillin Resistant Staphylococcus aureus ( MRSA ),” Media Farm. Indones., vol. 13, no. 2, pp. 1347–1353, 2018, [Online]. Available: https://repository.stifar.ac.id/Repository/article/view/85.
W. Wulandari and E. Refryliana, “Antibacterial activity test of sweet arum mango peel extract gel preparation (Mangifera indica L.) against growth methicillin resistant staphylococcus aureus,” J. Heal. Manag. Pharm. Explor., vol. 1, no. 1, pp. 25–34, Jan. 2023, doi: 10.52465/johmpe.v1i1.134.
M. Djaeni, N. Ariani, R. Hidayat, and F. D. Utari, “Ekstraksi Antosianin dari Kelopak Bunga Rosella (Hibiscus sabdariffa L.) Berbantu Ultrasonik: Tinjauan Aktivitas Antioksidan Ultrasonic Aided Anthocyanin Extraction of Hibiscus sabdariffa L. Flower Petal: Antioxidant Activity,” J. Apl. Teknol. Pangan, vol. 6, no. 3, p. 71, 2017, doi: 10.17728/jatp.236.
E. Subroto, R. Andoyo, and R. Indiarto, “Solid Lipid Nanoparticles: Review of the Current Research on Encapsulation and Delivery Systems for Active and Antioxidant Compounds,” Antioxidants, vol. 12, no. 3, p. 633, 2023, doi: 10.3390/antiox12030633.
A. Aminah, N. Tomayahu, and Z. Abidin, “PENETAPAN KADAR FLAVONOID TOTAL EKSTRAK ETANOL KULIT BUAH ALPUKAT (Persea americana Mill.) DENGAN METODE SPEKTROFOTOMETRI UV-VIS,” J. Fitofarmaka Indones., vol. 4, no. 2, pp. 226–230, 2017, doi: 10.33096/jffi.v4i2.265.
H. Asmorowati, “Penetapan kadar flavonoid total buah alpukat biasa (Persea americana Mill.) dan alpukat mentega (Persea americana Mill.) dengan metode spektrofotometri UV-Vis,” J. Ilm. Farm., vol. 15, no. 2, pp. 51–63, 2019, doi: 10.20885/jif.vol15.iss2.art1.
D. Dominica and D. Handayani, “Formulasi dan Evaluasi Sediaan Lotion dari Ekstrak Daun Lengkeng (Dimocarpus Longan) sebagai Antioksidan,” J. Farm. Dan Ilmu Kefarmasian Indones., vol. 6, no. 1, p. 1, 2019, doi: 10.20473/jfiki.v6i12019.1-7.
A. Arisanty, S. Sinala, M. Sukmawaty, and A. Masna, “Physical Formulation and Quality Preparations of Dry Herb Essence Gotu kola (Centellaasiatica (L.) Urban) With Concentration Variation using Span 60 and Tween 60 Emulgators,” Media Farm., vol. XVI, no. 1, pp. 1–23, 2020, doi: 10.32382/mf.v16i1.1424.
A. D. Puspitasari and E. I. Kusuma Wardhani, “Evaluasi Karakteristik Fisika-Kimia dan Nilai SPF Lotion Tabir Surya Ekstrak Daun Kersen (Muntingia calabura L.),” J. Ris. Teknol. Ind., vol. 12, no. 2, pp. 150–158, 2018, doi: 10.26578/jrti.v12i2.4242.
P. Molyneux, “The use of the stable radical Diphenylpicrylhydrazyl (DPPH) for estimating antioxidant activity,” vol. 26, Nov. 2003.