Antibacterial activity test of sweet arum mango peel extract gel preparation (Mangifera indica L.) against growth methicillin resistant staphylococcus aureus
Article Sidebar
Main Article Content
Abstract
Inappropriate use of antibiotics can make bacteria’s reistance that cause skin diseases, the example is acne. Acne tretment usually uses synthethic drugs that causes side effects, so the alternative are used by plants that come from nature. On of the plats that has the potential as an antibacterial is the arum manis mango (Mangifera indica L.) because contains compounds that can inhibit the growth of Mathicillin Resistant Staphylococcus aureus. The research of this study was to determine the antibacterial activity of extract gel’s arum manis mango peel to c. Extract of arum manis mango peel was obtained remaserated using 70% ethanol solvent. The extract obtined were phytochemicel screening and affirmation tests using the TLC (Thin Layer Chromatography) method to ensure the compounds contained. Arum manis mango peel is preparation of gel with a concentration of 5%, 10%, 15%, 20%, 25%. The results showed that extract of arum manis mango peel preparation gel with concentrations of 5%, 10%, 15%, 20%, 25%. The results showed that extract of arum manis peel preparation gel with concentration 5%, 10%, 15%, 20%, 25% showed significant difference in potential of antibacterial.
Article Details
References
J. K. Nuzantry and R. I. Widayati, “Efektivitas campuran ekstrak aloe vera dan olive oil dalam formulasi pelembab pada kekeringan kulit.” Faculty of Medicine, 2015.
R. Mahmudah, T. U. Soleha, and C. N. Ekowati, “Identifikasi methicillin-resistant staphylococcus aureus (mrsa) pada tenaga medis dan paramedis di ruang intensivecare unit (icu) dan ruang perawatan bedah rumah sakit umum daerah Abdul Moeloek,” J. Major., vol. 2, no. 4, 2013.
Afifurrahman, “Pola Kepekaan Bakteri Staphylococcus aureus terhadap Antibiotik Vancomycin di RSUP Dr. Mohammad Hoesin Palembang.,” Maj. Kedokt. Sriwijaya, Th. 46, No. 4, 2014. doi: 10.36706/mks.v46i4.2716. https://doi.org/10.36706/mks.v46i4.2716
Y. Arista, N. Kumesan, P. V. Y. Yamlean, and H. S. Supriati, “Formulasi Dan Uji Aktivitas Gel Antijerawat Ekstrak Umbi Bakung (Crinum Asiaticum L.) Terhadap Bakteri Staphylococcus Aureus Secara in Vitro,” PHARMACON J. Ilm. Farm. – UNSRAT, vol. 2, no. 02, pp. 2302–2493, 2013. doi: 10.35799/pha.2.2013.1552. https://doi.org/10.35799/pha.2.2013.1552
R. I. Depkes, “Analisis Obat Tradisional,” Jilid I. Jakarta Dep. Kesehat. Republik Indones. Hlm, vol. 72, p. 74, 1987.
R. Marjoni, “Dasar-dasar fitokimia. Jakarta: CV,” Trans Info Media, 2016.
J. B. Harborne, Metode Fitokimia Penuntun Cara Modern Menganalisis Tumbuhan, 2nd ed. Bandung: ITB, 1987.
R. I. Depkes, “Farmakope indonesia edisi IV,” Jakarta Dep. Kesehat. Republik Indones., vol. 45, 1995.
T. Robinson, “Kandungan organik tumbuhan tinggi,” 1995.
R. M. Baird, N. A. Hodges, and S. P. Denyer, Handbook of microbiological quality control in pharmaceuticals and medical devices. CRC Press, 2000.
S. G. Ganiswara, “Farmakologi dan terapi Edisi 4, jakarta: Bagian Farmakologi FKUI.” Hal, 1995.
Y. Yuwono, “Identifikasi Staphylococcal Cassette Chromosome Mec Methicillin Resistant Staphylococcus aureus dengan Polymerase Chain Reaction,” Maj. Kedokt. Bandung, vol. 43, no. 2, pp. 60–65, 2011. doi: 10.15395/mkb.v43n2.52. http://dx.doi.org/10.15395/mkb.v43n2.52
O. H. Naibaho, P. V. Y. Yamlean, and W. Wiyono, “Pengaruh basis salep terhadap formulasi sediaan salep ekstrak daun kemangi (Ocimum sanctum L.) pada kulit punggung kelinci yang dibuat infeksi Staphylococcus aureus,” Pharmacon, vol. 2, no. 2, 2013. doi: 10.35799/pha.2.2013.1553. https://doi.org/10.35799/pha.2.2013.1553
A. Garg, D. Aggarwal, S. Garg, and A. K. Singla, “Spreading of semisolid formulations: an update,” Pharm. Technol. North Am., vol. 26, no. 9, p. 84, 2002.
J. I. G. P. K. Zats, No Title. Newyork: Marcel Dekker, 1996.
S. M. Wasitaatmaja, Penuntun Ilmu Kosmetik Medik. Jakarta: UII, 1997.